Product Introduction
CAS Number: 850-52-2
Standard: In-house standard
Dinoprost Tromethamine, also known as Dinoprost trometamol, is an active pharmaceutical ingredient (API) used in veterinary medicine. It is derived from prostaglandin F2α (PGF2α), a naturally occurring hormone found in animals, and is primarily used in the reproductive management of livestock, particularly in cattle and swine.
Applications
The chemical formula of Dinoprost Tromethamine is C20H34O5N and its CAS number is 850-52-2. It is a synthetic analog of PGF2α and exhibits similar biological activity. The tromethamine salt form of Dinoprost enhances the stability and solubility of the compound, making it suitable for formulation and administration.
Dinoprost Tromethamine acts as a potent luteolytic agent, meaning it promotes the regression of the corpus luteum (a temporary endocrine structure) in the reproductive system of animals. By inducing luteolysis, Dinoprost initiates the estrous cycle, facilitates synchronization of estrus, and helps manage reproductive disorders in livestock.
In cattle, Dinoprost Tromethamine is commonly used for estrus synchronization, breeding programs, and controlling the reproductive cycle. It can induce heat (estrus) in non-cycling cows, shorten the estrous cycle, and facilitate timed insemination. Additionally, it is employed in the treatment of various reproductive conditions such as pyometra (pus-filled uterus) and retained placenta.
In swine, Dinoprost Tromethamine is used to induce abortion, terminate pregnancy, or control the timing of farrowing (giving birth). It is particularly useful in cases where gestation needs to be synchronized in a group of sows for efficient management and production.
The administration of Dinoprost Tromethamine is typically done via intramuscular injection or intrauterine infusion. The dosage and timing depend on the specific reproductive goals and the animal's condition, and should be determined by a veterinarian experienced in reproductive management.
In conclusion, Dinoprost Tromethamine API is a valuable tool in veterinary reproductive medicine. Its ability to regulate and synchronize reproductive processes in livestock, such as estrus induction and luteolysis, contributes to improved breeding efficiency and reproductive management practices.
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