Gonadorelin Acetate:
Mechanism, Applications, and Product Profile
Gonadorelin Acetate (CAS 71447-49-9) is a synthetic form of gonadotropin-releasing hormone (GnRH), engineered to mimic the natural hormone produced by the hypothalamus. By stimulating the pituitary gland to release luteinizing hormone (LH) and follicle-stimulating hormone (FSH), it plays a pivotal role in regulating reproductive function.
As a highly purified peptide API, Gonadorelin Acetate is widely used in the development of infertility therapies, hormone-regulation drugs, and diagnostic agents that assess pituitary and gonadal activity.
Product Overview
Gonadorelin Acetate is supplied as a lyophilized peptide powder with consistent purity and batch reproducibility. It is ideal for pharmaceutical manufacturers, formulation developers, contract labs, and biotech companies seeking a dependable hormone-based starting material.
Key Specifications
- ▸ CAS Number: 71447-49-9
- ▸ Molecular Formula: C₅₇H₇₉N₁₇O₁₅
- ▸ Molecular Weight: ~1242.36 g/mol
- ▸ Appearance: White to off-white lyophilized powder
- ▸ Purity: ≥ 98% (HPLC); COA provided for every batch
- ▸ Solubility: Soluble in sterile water and standard peptide buffers
- ▸ Storage: 2–8 °C (routine); –20 °C (long-term)
- ▸ Packaging: Evaluation vials, commercial-scale, OEM options
Each batch includes impurity profile, stability data, and technical documentation, ensuring seamless integration into R&D or formulation workflows.
How Gonadorelin Acetate Works
Gonadorelin Acetate mimics endogenous GnRH, triggering controlled release of LH and FSH from the pituitary gland.
Physiological Effects
- ▸ LH release: Supports ovulation and testosterone production
- ▸ FSH release: Stimulates follicular growth and spermatogenesis
- ▸ HPG axis activation: Restores hormonal balance
Applications in Infertility and Hormonal Therapy
Infertility Treatment for Women
- ▸ Ovulation induction
- ▸ Hypogonadotropic hypogonadism
- ▸ Controlled ovarian stimulation
- ▸ Amenorrhea caused by GnRH deficiency
Infertility Treatment for Men
- ▸ Enhanced testosterone production
- ▸ Improved sperm development
- ▸ Treatment of delayed puberty
Diagnostic Use
- ▸ Pituitary responsiveness testing
- ▸ LH/FSH secretion evaluation
- ▸ HPG axis integrity assessment
Summary
Gonadorelin Acetate is a high-purity synthetic GnRH analog widely used in infertility treatment, endocrine therapy, and reproductive diagnostics. With robust documentation, flexible supply options, and predictable biological activity, it remains a trusted API for modern hormone-based therapeutics.
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