Cloprostenol Sodium Injection

Name: China Customized Cloprostenol Sodium Injection Manufacturers Suppliers Factory
Brand: Origin
SKU: 294184461

Veterinary Drug

Veterinary Drug Name

Generic Name: Cloprostenol Sodium Injection

Main Ingredient

Cloprostenol Sodium

Description / Appearance

This product is a colorless, clear liquid.

Pharmacological Action

Cloprostenol Sodium is a synthetic analogue of prostaglandin F2α with the following effects:

▸ Luteolytic effect: Rapid regression of the corpus luteum and inhibition of its secretion.

▸ Uterotonic effect: Direct stimulation of uterine smooth muscle, causing uterine contractions and cervical relaxation.

Effects on Animals

▸ In animals with normal estrous cycles: estrus usually occurs within 2–5 days after administration.

▸ In pregnant cows at 10–150 days gestation: abortion usually occurs 2–3 days after injection.

Indications and Usage

Prostaglandins have a strong luteolytic effect and directly stimulate uterine smooth muscle. They are mainly used for estrus synchronization in cows and induction of parturition in pregnant sows.

Dosage and Administration

Intramuscular (IM) Injection

▸ Cattle: 2–3 ml per dose.

▸ Pigs: 0.5–1 ml on day 112–113 of pregnancy.

Adverse Reactions

Use during late pregnancy may increase the risk of dystocia (difficult birth) and may result in decreased efficacy.

Precautions

1. Contraindication: Do not use in pregnant animals unless intended for induction of parturition or termination of pregnancy.

2. Induction of Farrowing: Use no earlier than 2 days before the expected farrowing date.

3. Human Safety: This product can induce abortion or acute bronchospasm in humans. Pregnant women, women of childbearing age, asthmatics, and persons with respiratory diseases must exercise extreme caution.

4. Accidental Exposure: If breathing difficulties occur due to accidental inhalation or injection, use a fast-acting bronchodilator and seek medical attention.

5. Dermal Absorption: Easily absorbed through the skin. Wear rubber or disposable gloves during handling. Wash hands thoroughly with soap and water after use and before eating/drinking. Flush skin immediately with clear water if contact occurs.

6. Drug Interactions: Do not use concurrently with non-steroidal anti-inflammatory drugs (NSAIDs).

7. Disposal: Empty vials should be deeply buried or incinerated. Dispose of waste in approved facilities. Do not dispose of undiluted product on-site. Prevent contamination of water, feed, and food.