Cloprostenol Sodium Injection Package Insert
Veterinary Drug
Veterinary Drug Name
Generic Name: Cloprostenol Sodium Injection
Main Ingredient
Cloprostenol Sodium
Description / Appearance
This product is a colorless, clear liquid.
Pharmacological Action
Cloprostenol Sodium is a synthetic analogue of prostaglandin F2α with the following effects:
▸ Luteolytic effect: Rapid regression of the corpus luteum and inhibition of its secretion.
▸ Uterotonic effect: Direct stimulation of uterine smooth muscle, causing uterine contractions and cervical relaxation.
▸ In animals with normal estrous cycles: estrus usually occurs within 2–5 days after administration.
▸ In pregnant cows at 10–150 days gestation: abortion usually occurs 2–3 days after injection.
Indications and Usage
Prostaglandins have a strong luteolytic effect and directly stimulate uterine smooth muscle. They are mainly used for estrus synchronization in cows and induction of parturition in pregnant sows.
Dosage and Administration
Intramuscular (IM) injection:
▸ Cattle: 2–3 ml per dose.
▸ Pigs: 0.5–1 ml on day 112–113 of pregnancy.
Adverse Reactions
Use during late pregnancy may increase the risk of dystocia (difficult birth) and may result in decreased efficacy.
Precautions
▸ Contraindication: Do not use in pregnant animals unless intended for induction of parturition or termination of pregnancy.
▸ Induction of Farrowing: Use no earlier than 2 days before the expected farrowing date.
▸ Human Safety: This product can induce abortion or acute bronchospasm in humans.
▸ Accidental Exposure: Use bronchodilator and seek medical attention.
▸ Dermal Absorption: Wear rubber or disposable gloves.
▸ Drug Interactions: Do not use concurrently with NSAIDs.
▸ Disposal: Dispose of waste safely and prevent contamination.
Product Information
Specification
Calculated as C22H29ClO6: 20ml:2mg.
Packaging
1 vials per box.
Storage
Store in a sealed, cool and dark place.
Shelf Life
2 years.
Manufacturer Information
Xiamen Origin Biotech Co., Ltd.
Address: No. 9-5 Xianghai 2nd Road, Xiang'an Torch Hi-tech Industrial Development Zone, Xiamen, China
Tel: +86-592-7073986
Postal Code: 361101
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