Product Introduction
CAS Number: 74150-27-9
Standard: In-house standard
Pimobendan is a chemical drug used to treat mild, moderate or severe congestive heart failure caused by atrioventricular insufficiency or myocardial hypertrophy in dogs.
Applications
Pimobendan is a medication that has been used to treat heart failure in dogs since its approval by the FDA in 2007, it is a benzimidazole-pyridazinone derivative, labeled for use in dogs to manage congestive heart failure (CHF) resulting from dilated cardiomyopathy (DCM) or degenerative mitral valve disease (DMVD) in the United States. On the basis of its positive inotropic effects combined with arteriovenous dilation, it is classified as an inodilator.
Pimobendan seems to be safe and well tolerated. Reported adverse effects are relatively rare and are typically limited to gastrointestinal upset associated with the chewable tablets. Significant overdose has reportedly resulted in pimobendan toxicity, manifested as severe tachycardia and mild changes in blood pressure.
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