D-Cloprostenol Sodium
Pure Dextrorotatory Isomer for Superior Luteolytic Efficacy
D-Cloprostenol Sodium is a highly potent synthetic prostaglandin analogue. As the optically active dextrorotatory isomer of Cloprostenol, it possesses significantly greater luteolytic activity than the racemic mixture. It is a cornerstone of modern veterinary reproductive management, human obstetrics, and specialized ophthalmic care.
Technical Specifications
| CAS Number | 62561-03-9 |
| Molecular Formula | C₂₂H₂₈ClNaO₆ |
| Appearance | White to off-white crystalline powder |
| Solubility | Soluble in water, ethanol, and methanol |
| Pharmacological Class | PGF2α Receptor Agonist |
Veterinary Reproductive Management
By inducing the rapid regression of the corpus luteum, D-Cloprostenol Sodium allows for precision control in agricultural breeding:
- Estrus synchronization for Timed AI
- Treatment of chronic endometritis
- Induction of parturition
- Controlled farrowing in sows
- Management of persistent corpus luteum in mares
- Herd fertility optimization
Human Medical & Specialized Uses
• Obstetric Care: Used under strict clinical supervision to induce labor in post-term or high-risk pregnancies by promoting controlled uterine contractions.
• Ophthalmology: Employed in the treatment of open-angle glaucoma and ocular hypertension by increasing uveoscleral outflow to lower intraocular pressure.
• Research Frontiers: Ongoing investigation into its role in cancer cell signaling (prostate/breast) and anti-fibrotic pathways in pulmonary tissue remodeling.
Summary
D-Cloprostenol Sodium represents the evolution of prostaglandin therapy, offering higher receptor affinity and lower required dosages than traditional analogues. Its diverse utility-from optimizing global livestock production to preventing vision loss-underscores its status as an indispensable bioactive compound.
Concerning Origin Biotech
Origin Biotech is a leader in the synthesis of high-purity prostaglandin isomers. We provide the veterinary and pharmaceutical industries with validated APIs, ensuring consistent clinical performance through rigorous analytical standards.
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