(-)-Corey Lactone Diol

CAS Number: 32233-40-2

Standard: In-house

(-)-Corey Lactone Diol is a chiral building block for organic synthesis, with high enantiomeric purity and broad applicability in drug research and development.

Corey lactone diol, also known as 4-(2-hydroxyethyl)-2-cyclopenten-1-one, is a valuable intermediate in organic chemistry. It contains a reactive carbonyl group and a hydroxyl group, which makes it a versatile building block for the synthesis of a wide range of organic compounds. In this article, we will discuss some of the applications of Corey lactone diol.

1. Synthesis of pharmaceuticals

Corey lactone diol can be used as a key intermediate in the synthesis of various pharmaceuticals. For example, it is used in the synthesis of cephalosporins, which are antibiotics that have a broad spectrum of activity against Gram-negative bacteria. It is also used in the synthesis of prostacyclin analogs, which are used to treat pulmonary arterial hypertension and other cardiovascular diseases.

2. Synthesis of agrochemicals

Corey lactone diol is also a useful intermediate in the synthesis of agrochemicals, such as insecticides and fungicides. For example, it can be used in the synthesis of pyrethroids, which are a class of insecticides that are effective against a wide range of insect pests. It can also be used in the synthesis of fungicides, such as azoles, which are used to control fungal diseases in crops.

3. Synthesis of fragrances and flavors

Corey lactone diol can also be used in the synthesis of fragrances and flavors. For example, it can be used in the synthesis of γ-lactones, which have a characteristic sweet, creamy odor that is often used in perfumes and cosmetics. It can also be used in the synthesis of fruity flavors, such as peach, apricot, and strawberry.

4. Synthesis of polymers

Corey lactone diol can be used as a monomer in the synthesis of polymers. For example, it can be polymerized with other monomers, such as lactide, to form biodegradable polymers that have applications in packaging, biomedical devices, and other fields.

5. Synthesis of other organic compounds

Corey lactone diol can be used as a building block for the synthesis of a wide range of other organic compounds. For example, it can be used in the synthesis of amino acids, vitamins, and other bioactive molecules. It can also be used in the synthesis of dyes, pigments, and other specialty chemicals.
 

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