D-Cloprostenol Sodium API
Synthetic Prostaglandin F₂α Analogue for Veterinary Reproductive Management
D-Cloprostenol Sodium (CAS 62561-03-9) is a synthetic analogue of Prostaglandin F₂α widely used in veterinary medicine. Known for its potent luteolytic action, it is a core component in modern livestock reproductive management programs, helping synchronize estrus, regulate hormone levels, and support the treatment of reproductive disorders. The compound is produced according to in-house standards, ensuring high purity and consistency for veterinary pharmaceutical applications.
Chemical Characteristics
| Feature | Description |
|---|---|
| Chemical Formula | C₂₂H₂₉ClO₆ |
| Molecular Weight | Approx. 416.92 g/mol |
| Appearance | White to off-white crystalline powder |
| Solubility | Soluble in water, ethanol, and methanol |
| pH | Approximately neutral (pH ~7) |
| Storage | Cool, dry place at room temperature |
| Stability | Stable under recommended conditions |
| Standard | In-house standard |
Its stability, ease of handling, and good solubility make it suitable for injectable veterinary formulations.
Mechanism of Action
D-Cloprostenol Sodium induces luteolysis by promoting regression of the corpus luteum, resulting in reduced progesterone levels. This action triggers estrus synchronization, termination of pregnancy (species-specific), or restoration of normal reproductive cycles under controlled veterinary use.
Veterinary Applications
1. Estrous Synchronization
Improves artificial insemination efficiency and breeding control.
- Coordinated estrus cycles
- Reduced labor requirements
- Improved reproductive success
2.Reproductive Health Management
- Regression of luteal cysts
- Normalization of hormonal imbalance
- Restoration of fertility
3. Uterine Inflammation Control
- Enhanced uterine contractions
- Expulsion of inflammatory fluids
- Reduced infection duration
Conclusion
D-Cloprostenol Sodium is a powerful veterinary prostaglandin API that supports efficient breeding programs, improves reproductive health, and enhances herd productivity. Its proven luteolytic activity, stability, and reliability make it a cornerstone ingredient in modern livestock reproductive management.
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