Cetrorelix Acetate
Synthetic GnRH Antagonist API
CAS Number: 120287-85-6
Molar Mass: 1431.04 g/mol
Standard: In-house
Cetrorelix Acetate is a synthetic decapeptide and a potent Gonadotropin-Releasing Hormone (GnRH) antagonist. It works by blocking the action of natural GnRH at pituitary receptors, thereby inhibiting the release of Luteinizing Hormone (LH) and Follicle Stimulating Hormone (FSH). By delaying the LH surge, Cetrorelix effectively prevents premature ovulation, making it a key ingredient in assisted reproductive technology (ART).
Product Details
| Property | Description |
|---|---|
| Molar Mass | 1431.04 |
| Density | 1.42 ± 0.1 g/cm³ (Predicted) |
| Melting Point | >259°C (dec.) |
| Solubility | Slightly soluble in DMSO (heated), very slightly soluble in methanol |
| Appearance | Powder |
| Color | White to Off-White |
| pKa | 9.82 ± 0.15 (Predicted) |
| Storage | Store refrigerated |
How Cetrorelix Acetate Works
Cetrorelix competes with natural GnRH for pituitary receptors. By blocking these receptors, it suppresses the secretion of LH and FSH, delaying follicular maturation and preventing early ovulation. This precise hormonal control is essential during controlled ovarian stimulation (COS) in IVF and other ART procedures.
Applications
1. Assisted Reproductive Technology (ART)
Cetrorelix Acetate is widely used in IVF protocols to:
- ▸ Prevent premature LH surge
- ▸ Delay ovulation
- ▸ Improve the synchronization of follicle development
- ▸ Reduce the risk of premature release of immature follicles
- ▸ Increase the chances of successful egg retrieval and conception
By maintaining better hormonal control, it supports improved outcomes in fertility treatments.
Why Choose Our Cetrorelix Acetate?
1. Extensive Production Experience
With over 10 years of pharmaceutical manufacturing experience, our team provides professional support and reliable API solutions.
2. GMP-Compliant Manufacturing System
Our facility spans 2,523 m², including a 365 m² Class D clean area, constructed to meet strict GMP standards ensuring product purity and consistency.
3. Rigorous Quality Control
From raw material selection to environmental monitoring, every step is strictly controlled to deliver high-quality, stable, and safe products.
4. Excellent Customer Support
We prioritize customer satisfaction by providing:
- ▸ Full documentation for product registration
- ▸ Tailored solutions for specific requirements
- ▸ Fast, clear, and professional communication
FAQ
Q1: In which fields can this product be used?
A: Our Cetrorelix Acetate is widely applied in reproduction, endocrinology, and gynecology, for both human and veterinary uses.
Q2: Are you a manufacturer or a trading company?
A: We are a direct manufacturer with a complete production line, enabling us to offer competitive factory pricing while ensuring consistent quality.
B2B Manufacturing Excellence
Supplying high-purity synthetic peptides with documented quality and full regulatory support.
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