Terlipressin Acetate

Synthetic Vasopressin Analogue for Critical Care

Molecular Formula: C₅₂H₇₄N₁₆O₁₅S₂
Molar Mass: 1227.37

Standard: In-house

Terlipressin Acetate is a synthetic long-acting vasopressin analogue widely used in emergency and critical-care medicine. As a prodrug, Terlipressin becomes active only after metabolism, offering controlled, prolonged therapeutic effects. It plays a vital role in the management of variceal bleeding, hepatorenal syndrome, and life-threatening circulatory conditions.

Physicochemical Properties

Property	Details
Density	1.46 ± 0.1 g/cm³ (Predicted)
Melting Point	>170°C (dec.)
Boiling Point	1824.0 ± 65.0°C (Predicted)
Flash Point	1056.9°C
Solubility	Slightly soluble in DMSO and Methanol
Vapor Pressure	0 mmHg at 25°C
Appearance	Solid
Color	White
pKa	9.90 ± 0.15 (Predicted)
Storage Conditions	Store under −20°C, in an inert atmosphere, protected from light

Applications

1. Treatment of Esophageal Variceal Bleeding

Terlipressin Acetate is the first-line medication in emergency management of esophageal variceal hemorrhage.

Clinically proven to reduce portal pressure

Only drug confirmed to significantly prolong survival time in patients with variceal bleeding

2. Hepatorenal Syndrome (HRS) and Liver Support

Terlipressin is widely used in liver-failure management due to its ability to:

▸ Improve renal perfusion
▸ Enhance liver and kidney function
▸ Extend the stability period for patients awaiting liver transplantation

3. Shock Management & Critical Care

Terlipressin Acetate is effective in:

▸ Refractory shock
▸ Cardiopulmonary resuscitation support (CPR)
▸ Pediatric cardiac arrest
▸ Intraoperative hypotension

Its potent vasoconstrictive properties make it highly valuable in emergency and perioperative care.

Why Choose Us

1. 10+ Years of Manufacturing Expertise

With over a decade of experience in pharmaceutical production, we ensure consistent quality and technical support.

2. GMP-Compliant Production Facility

▸ Total workshop area: 2,523 m²
▸ 365 m² Class D cleanroom
▸ Fully aligned with modern GMP standards

3. Rigorous Quality Control

▸ Raw material verification
▸ Instrument calibration
▸ Complete batch traceability

4. Dedicated Customer Support

We offer:

▸ Registration documents (DMF, COA, MSDS, etc.)
▸ Customization and tailored solutions
▸ Fast response and professional service

FAQ

Q: Have you exported your products internationally?

A: Yes. We export to India, the Middle East, South America, and various EU countries, receiving consistently high customer satisfaction.

Q: How do you ensure product quality?

A: Through a fully established quality assurance system, covering every stage-from raw material sourcing to final product release-to guarantee purity, safety, and consistency.