Product Introduction
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CAS Number: 61489-71-2
Standard: In-house
Human Menopausal Gonadotrophin (hMG) is a critical medication in the field of reproductive medicine, helping both women and men overcome certain types of infertility. Its administration requires careful medical supervision to maximize efficacy and minimize potential risks
Physical Features
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| Feature | Description |
| Source | Derived from the urine of postmenopausal women |
| Composition | Contains a combination of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) |
| Form | Lyophilized powder or solution |
| Administration Route | Subcutaneous or intramuscular injection |
| Primary Uses | Fertility treatments: |
| - Stimulate ovarian follicle development in women | |
| - Induce ovulation | |
| - Stimulate spermatogenesis in men with hypogonadotropic hypogonadism | |
| Mechanism of Action | Mimics the action of natural FSH and LH: |
| - FSH: Stimulates growth and maturation of ovarian follicles and spermatogenesis | |
| - LH: Triggers ovulation and supports corpus luteum function in women; stimulates testosterone production in men | |
| Dosage | Variable, individualized based on response to therapy; monitored through ultrasound and hormone levels |
| Common Side Effects | Local injection site reactions, headache, abdominal discomfort, bloating |
| Serious Side Effects | Ovarian hyperstimulation syndrome (OHSS), multiple pregnancies (twins, triplets) |
| Contraindications | Primary ovarian failure, uncontrolled thyroid or adrenal dysfunction, hormone-sensitive tumors |
| Monitoring | Regular monitoring required: |
| - Women: Ultrasound, serum estradiol levels | |
| - Men: Serum testosterone levels | |
| Regulatory Status | Prescription only, regulated by FDA (USA), EMA (Europe), etc. |
Applications
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Human Menopausal Gonadotropin (HMG), also known as menotropin, is a fertility medication derived from the urine of postmenopausal women. It contains a mixture of two important hormones: follicle-stimulating hormone (FSH) and luteinizing hormone (LH).
HMG is commonly used in fertility treatments such as in vitro fertilization (IVF) and intrauterine insemination (IUI). Its primary functions include:
- Stimulating ovulation in women who do not ovulate naturally (anovulation).
- Promoting the development of multiple ovarian follicles in preparation for egg retrieval during IVF.
In men, HMG can be utilized to stimulate sperm production in cases of hypogonadotropic hypogonadism, a condition where low levels of gonadotropins lead to infertility.
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