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Human Menopausal Gonadotrophin HMG CAS 61489-71-2

Human Menopausal Gonadotrophin HMG CAS 61489-71-2

Human Menopausal Gonadotrophin (hMG) is a critical medication in the field of reproductive medicine, helping both women and men overcome certain types of infertility. Its administration requires careful medical supervision to maximize efficacy and minimize potential risks

Product Introduction

Product Introduction

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CAS Number: 61489-71-2

Standard: In-house

Human Menopausal Gonadotrophin (hMG) is a critical medication in the field of reproductive medicine, helping both women and men overcome certain types of infertility. Its administration requires careful medical supervision to maximize efficacy and minimize potential risks

 

Physical Features

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Feature Description
Source Derived from the urine of postmenopausal women
Composition Contains a combination of follicle-stimulating hormone (FSH) and luteinizing hormone (LH)
Form Lyophilized powder or solution
Administration Route Subcutaneous or intramuscular injection
Primary Uses Fertility treatments:
- Stimulate ovarian follicle development in women
- Induce ovulation
- Stimulate spermatogenesis in men with hypogonadotropic hypogonadism
Mechanism of Action Mimics the action of natural FSH and LH:
- FSH: Stimulates growth and maturation of ovarian follicles and spermatogenesis
- LH: Triggers ovulation and supports corpus luteum function in women; stimulates testosterone production in men
Dosage Variable, individualized based on response to therapy; monitored through ultrasound and hormone levels
Common Side Effects Local injection site reactions, headache, abdominal discomfort, bloating
Serious Side Effects Ovarian hyperstimulation syndrome (OHSS), multiple pregnancies (twins, triplets)
Contraindications Primary ovarian failure, uncontrolled thyroid or adrenal dysfunction, hormone-sensitive tumors
Monitoring Regular monitoring required:
- Women: Ultrasound, serum estradiol levels
- Men: Serum testosterone levels
Regulatory Status Prescription only, regulated by FDA (USA), EMA (Europe), etc.

 

Applications

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Human Menopausal Gonadotropin (HMG), also known as menotropin, is a fertility medication derived from the urine of postmenopausal women. It contains a mixture of two important hormones: follicle-stimulating hormone (FSH) and luteinizing hormone (LH).

 

HMG is commonly used in fertility treatments such as in vitro fertilization (IVF) and intrauterine insemination (IUI). Its primary functions include:

- Stimulating ovulation in women who do not ovulate naturally (anovulation).
- Promoting the development of multiple ovarian follicles in preparation for egg retrieval during IVF.

 

In men, HMG can be utilized to stimulate sperm production in cases of hypogonadotropic hypogonadism, a condition where low levels of gonadotropins lead to infertility.

 

 

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