Product Introduction
CAS Number: 9039-53-6
Standard: In-house
Urokinase remains an important tool in the management of thrombotic conditions, offering a life-saving intervention for patients experiencing severe clot-related issues.
Applications
Strong clot-dissolving enzyme urokinase is frequently utilized in medical settings to address a variety of blood clot-related problems. In order to restore regular blood flow, it dissolves fibrin clots.
Pulmonary Embolism
A dangerous illness known as pulmonary embolism (PE) occurs when a blood clot blocks one or more pulmonary arteries. By dissolving these clots using urokinase, consequences like respiratory failure and mortality can be avoided and normal blood flow and oxygenation can be restored.
Deep Vein Thrombosis
Blood clots in the deep veins, generally in the legs, cause deep vein thrombosis (DVT). These clots may become painful, swollen, and dislodge, which could result in a lung embolism. Urokinase aids in the dissolution of these clots, reducing symptoms and averting grave DVT consequences.
Myocardial Infarction
Urokinase can be used to break up blood clots that are obstructing coronary arteries and cause acute myocardial infarctions, or heart attacks. By doing so, the damaged portion of the heart muscle is less damaged and the prognosis of the patient is enhanced. Although tissue plasminogen activator (tPA) is a more widely utilized drug, urokinase is still an effective treatment choice in some therapeutic settings.
Peripheral Arterial Occlusion
Blockages in peripheral arteries, which frequently affect the limbs, are known as peripheral arterial occlusion. These clots are broken up by urokinase, which relieves ischemia and stops tissue loss or damage. In order to maintain limb function and restore blood flow, prompt therapy is necessary.
Catheter-Associated Thrombosis
Patients who have central venous catheters frequently have catheter-related thrombosis as a problem. To ensure catheter patency and functionality, urokinase can be directly injected into the catheter to dissolve clots.
Occluded Arteriovenous Fistulas or Grafts
Clots can obstruct arteriovenous fistulas or grafts in patients receiving hemodialysis. These obstructions are removed with urokinase, preserving the arterial access required for dialysis.
In conclusion, urokinase plays a critical role in the treatment of thrombotic disorders, offering therapies that can save lives by efficiently breaking up clots and reestablishing normal circulation. Its many uses demonstrate how important it is to contemporary medical practice.
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