Dexmedetomidine Hydrochloride for Human CAS 145108-58-3

Dexmedetomidine Hydrochloride for Human CAS 145108-58-3

CAS Number: 145108-58-3
Complies with in-house standard.
Dexmedetomidine Hydrochloride is a sedative and anesthetic drug used to reduce anxiety and stress in patients who are undergoing medical procedures

Product Introduction

Dexmedetomidine Hydrochloride

High-Selectivity α₂-Adrenoceptor Agonist for Clinical Sedation

Dexmedetomidine Hydrochloride is a highly selective α₂-adrenoceptor agonist widely used in clinical and pharmaceutical settings for its potent sedative and anesthetic-sparing effects. It effectively reduces patient anxiety, stress, and the required dosage of other anesthetic agents.

Chemical & Physical Properties

Molecular Formula: C₁₃H₁₇ClN₂

Molar Mass: 236.74 g/mol

Density: 1.17 g/cm³

Melting Point: 156.5–157.5 °C

Boiling Point: 381.9 °C (760 mmHg)

Flash Point: 191.3 °C

Vapor Pressure: 1.08 × 10⁻⁵ mmHg at 25 °C

Solubility Profile

Dexmedetomidine Hydrochloride demonstrates excellent solubility, making it suitable for pharmaceutical formulation:

Water: 100 mM

DMSO: 48 mg/mL

Ethanol: 48 mg/mL

Appearance & Storage

Form: Crystalline powder

Color: White to off-white

Storage Conditions: 2–8 °C

Pharmacological Profile

Dexmedetomidine Hydrochloride is a highly selective α₂-adrenoceptor agonist with strong sedative properties. It significantly reduces the need for additional anesthetic agents, supporting safer and more controlled sedation protocols.

Applications & Uses

▸ Intensive Care Units (ICUs)

▸ Operating Rooms

▸ Procedural sedation

Key Benefits

▸ Reduces anxiety and stress

▸ Minimizes anesthetic dosage requirements

▸ Improves patient comfort and pain control

It is commonly administered pre-operatively, intra-operatively, and post-operatively, often in combination with other therapeutic agents.

Administration

Dexmedetomidine Hydrochloride may be administered via various clinical routes depending on medical requirements. It can be used as a single dose or multiple doses and is often combined with other sedative or anesthetic agents.

Our Strengths

1. Complete Manufacturing System
2,523 m² GMP-compliant facility with 365 m² Class D cleanroom.

2. Strict Quality Control
Comprehensive monitoring from raw materials to environmental controls.

3. Customer-Focused Service
Full technical support, regulatory documentation, and customized solutions.

Frequently Asked Questions (FAQ)

 

Q1: What are the main application fields of your products?
A: Our products are widely used in reproduction, endocrinology, and gynecology for both human and veterinary applications.

 

Q2: How are your products shipped?
A: Products are shipped primarily by air freight with full insurance coverage to ensure safe delivery.

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